Aspadol (Tapentadol) 100 mg is definitely recommended to treat persistent pain. Chronic pain is a form of pain that persists for weeks, months, or even years and has a major influence on a person’s quality of life. Aspadol, which contains the active component Tapentadol, is one of the drugs used to treat chronic pain efficiently. Tapentadol works by binding to opioid receptors in the brain and spinal cord, affecting how your body perceives and responds to pain signals. It also has effects on the neurotransmitters serotonin and norepinephrine, which can enhance its pain-relieving qualities.